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warfarin

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Official code for WarfaRisk — a reproducible, ancestry-stratified ML pipeline for warfarin dose prediction on the IWPC pharmacogenomic cohorts. Best model: MAE 8.55 mg/week, R²=0.475 (IWPC-6256) / R²=0.480 (IWPC-1780). Nested clinical/genetic ablation, conformal calibration with subgroup fairness reporting, SHAP/EBM explainability.

  • Updated Aug 10, 2026
  • Python

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