Miniprotein and antibody design pipeline for ESMFold2
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Updated
Jul 19, 2026 - Python
Miniprotein and antibody design pipeline for ESMFold2
Code for NeurIPS 2023 paper "AVIDa-hIL6: A Large-Scale VHH Dataset Produced from an Immunized Alpaca for Predicting Antigen-Antibody Interactions"
Code for NeurIPS 2024 paper "A SARS-CoV-2 Interaction Dataset and VHH Sequence Corpus for Antibody Language Models"
Small, fast, fully differentiable antibody Fv structure predictor in JAX. ~0.76M parameters, matches IgFold on CDR-H3, folds an Fv in ~0.8s on CPU.
For NBsTem Webserver
Build a structural nanobody library from the PDB: mine RCSB for nanobody/VHH entries, split nanobody and antigen chains, renumber and superpose in headless PyMOL
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