A toolkit developed to predict and analyze PROTAC-mediated ternary complexes using AlphaFold3 and Boltz-1.
PROTAC-Splitter is a machine learning framework designed for automated annotation of PROTAC substructures.
Predicting PROTAC protein degradation activity via machine learning.
Empirical evaluation of which public-data features actually predict PROTAC E3-ligase tractability — and which merely track how well-studied a ligase is.
End-to-end computational framework for designing cancer identity reversion therapies: scRNA-seq → Waddington attractor mapping → epigenetic switch set prediction → TCIP bifunctional molecule design
Arvinas — independent third-party profile of a public API surface, by API Evangelist. Arvinas is a clinical-stage biopharmaceutical company (NASDAQ: ARVN) headquartered in New Haven, Connecticut, developing targeted protein degradation therapeutics using its proprietary PROTAC (proteolysis targeting chimera) Discovery Engine.
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