molecular-diagnostics

Rapid-CNS2 Nextflow analysis pipeline

Public demo of MammaScope, a Streamlit-based tool for comparing immunohistochemistry (IHC) and MammaTyper molecular subtyping in breast cancer.

Workflow dedicated to mapping FDA-Cleared / Approved IVDs Nucleic Acid Amplification Tests (NAAT) to pathogens.

Species-specific primer design tool: NCBI retrieval → BLAST mismatch analysis → Primer3 design → Primer-BLAST validation. Desktop GUI (PySide6) + PDF/DOCX reports.

DesignLab — conservation-aware PCR/qPCR primer design: NCBI search, MAFFT alignment, conserved-block Primer3 design and in-silico validation, with every binding site visualised

Optimal AlphaMissense threshold based on VKGL variant classifications

An integrated computational pipeline for CRISPR-Cas13a (SHERLOCK) malaria diagnostics and trans-kingdom neuro-immune mapping, linking PfK13-driven pathogen detection to microglial homeostatic (CX3CR1/Iba1) set-points and Gut-Brain Axis (GBA) dysregulation.

Python script for qPCR analytic validation using Cq values of standard dilutions and technical replicates.

Crescendo Bioscience was a molecular-diagnostics company based in South San Francisco, known for Vectra DA (later Vectra), a multi-biomarker blood test that measures disease activity in rheumatoid arthritis.

Cellular Research, Inc. was a single-cell genomics company backed by Canaan Partners that developed molecular-indexing (its "Precise" assay) technology for high-throughput single-cell gene expression analysis.

Inflammatix is a molecular diagnostics company headquartered in Sunnyvale, California that reads the patient's own immune response to speed up decisions in emergency and critical care.

Shanghai Tellgen Life Sciences Co., Ltd. (Tellgen Corporation) is a Chinese in vitro diagnostics (IVD) company founded in 2003 and headquartered in Shanghai, focused on the research, development, manufacture, and distribution of high-end diagnostic reagents and instruments.

medxtmc — MEDx Translational Medicine Co., Ltd (MEDx TMC) is a Suzhou, China based precision medicine company founded in 2013, formerly QIAGEN (Suzhou) Translational Medicine. It is a leading provider of companion diagnostics (CDx) and total precision-medicine solutions, offering pharma services (biomarker discovery, target validation, patient…

Clear Labs builds automated next-generation sequencing (NGS) platforms that combine laboratory robotics, cloud software, and bioinformatics to deliver genomic data and actionable insights.

A tool that parses VKGL variant classification data from public releases, connects variants across time and provides insights by visualizing different aspects.

rdbio (仁度生物 / Rendo Biotech) — Rendo Biotech (仁度生物) is a Shanghai-based molecular diagnostics company founded in 2007 and listed on China's STAR Market (Science and Technology Innovation Board, stock code 688193).

Tempus AI (NASDAQ: TEM) is a precision medicine company that has built one of the world's largest libraries of de-identified clinical and molecular data, paired with an operating system to make that data accessible for diagnostics and research, starting with cancer.

BillionToOne is a molecular diagnostics company using proprietary single-molecule Quantitative Counting Template (QCT) technology to detect disease at the DNA level from cell-free DNA.

Complete Omics is a Baltimore, Maryland based, CLIA- and CAP-accredited molecular diagnostics company building ultra-deep, clinically reproducible proteomics and multi-omics testing.

Lucira Health (formerly Diassess Inc.) was a molecular diagnostics company based in Emeryville, California that developed single-use, disposable RT-LAMP test kits designed for at-home use.