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kosarHNajafi/README.md

MH Labs - AI-Driven Healthcare

πŸ‘‹ Hi, I'm Kosar HajNajafi

🧬 Systems Biology Researcher | Genetics & Bioinformatics | MH Labs πŸ“ Dubai, United Arab Emirates πŸ“§ hajnajafikosar@gmail.com πŸ”— LinkedIn β€’ GitHub

🧬 Research Interests

Genetics researcher integrating machine learning with high-throughput multi-omics data to dissect the molecular complexity of breast cancer, with a particular focus on immunogenomics and tumor-immune interactions in precision oncology. My work spans transcriptomic network analysis, cancer genomics, and computational modeling, and I'm currently expanding into single-cell and spatial approaches to characterize immune landscapes in tumors .

πŸŽ“ Education

University of Tabriz, Iran M.Sc. in Genetics (2024) β€” GPA 18.79/20, ranked 1st in class Thesis: Investigating the role of BCL11A in human breast tumors using a Systems Approach

University of Mohaghegh Ardabili, Iran B.Sc. in Cellular and Molecular Biology (2022) β€” GPA 19.59/20, ranked 1st in class

🧫 Bioinformatics & Laboratory Skills

πŸ§ͺ Wet Lab Techniques: Human Cell Culture β€’ MTT Assay β€’ Gel Electrophoresis β€’ PCR/RT-qPCR β€’ Western Blotting β€’ ELISA β€’ Flow Cytometry/FACS β€’ siRNA-mediated Gene Silencing

πŸ’» Bioinformatics Tools: BLAST/PSI-BLAST β€’ AlphaFold/ColabFold β€’ InterPro β€’ SignalP β€’ DeepTMHMM β€’ DeepLocPro β€’ IUPred3 β€’ NetSurfP β€’ HHpred β€’ PROST β€’ GenePattern β€’ Bioconductor

πŸ“š Databases & Resources: NCBI β€’ GEO β€’ TCGA β€’ METABRIC β€’ UCSC β€’ UniProt/UniParc β€’ PDB

πŸ“Š Programming & Data Analysis: Python β€’ R β€’ Git/GitHub β€’ Network Inference β€’ Pathway Analysis β€’ Machine Learning Basics

🌱 Currently Working On

  • πŸ”­ Developing pipelines to handle and interpret high-throughput biodata
  • 🧠 Learning single-cell analysis and machine learning approaches
  • 🧬 Automated Python pipeline for clustering Orthohantavirus tripartite segments using confidence-weighted metadata and Apache Parquet structures.
  • 🧫 Structural bioinformatics workflows including AlphaFold/ColabFold construct-level analysis and protein domain annotation

πŸ‘― Let's Connect

I'm looking to collaborate on computational biology projects, especially in cancer genetics and immunotherapy, and I'm actively seeking research assistantship or PhD opportunities in these areas. Feel free to reach out about voluntary collaboration in immunogenomics research or to discuss shared interests in genomics and precision medicine.

πŸ“§ hajnajafikosar@gmail.com πŸ”— GitHub Profile β€’ LinkedIn

πŸ“Š GitHub Overview

GitHub Stats

Popular repositories Loading

  1. GATA3_YBX1_ER-BC GATA3_YBX1_ER-BC Public

    GATA3 and YBX1 rewire ER-dependent metabolic programs and vulnerabilities in breast cancer

    R

  2. kosarHNajafi kosarHNajafi Public

    Systems Biology Researcher combining cellular assays and gene silencing with advanced data cleaning and machine learning. Experienced in building R/Python pipelines for transcriptomic cohort analys…