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hrrysprk/README.md

Hey, I'm Harpreet

Computational Biologist × ML Engineer × Musician

Portfolio Email Instagram


🧬 Decoding cancer genomes · 🚀 From space biology to clinical ML · 🎹 Making beats after midnight


About Me

💼   Computational Biologist, Software Development @ Michael Smith Genome Sciences Centre, BC Cancer
🎓   MDS @ UBC · BS-MS Biological Sciences @ IISER Mohali
🔬   3 peer-reviewed publications in Nature NPJ, BMC Genomics & Genetics
🌱   Building at the intersection of foundational models, RAG architectures, and clinical cancer genomics
🤖   AI-assisted development: Claude, Kiro IDE, Cursor Agent, multi-model validation
🎹   I make music when the pipelines are running


🛰️ Projects

Project Description Stack
🧬 GenBrowser Interactive 3D chromosome visualization with a novel surface accessibility algorithm Three.js TypeScript Vite
🔗 ChromApipe Cloud-native bioinformatics pipeline for chromosome accessibility analysis Nextflow Python AWS Batch Docker
🚀 spaceGen ML pipeline investigating how microgravity rewires gene expression in brain tissue Python Scanpy MLflow MuData
⛏️ MineScope Multi-modal mining microbiome platform integrating metagenomics, LiDAR terrain, and soil chemistry for AMD risk analysis Nextflow Python MetaPathways D3.js
📜 PolicyLens LLM-powered course policy QA system with intent classification and structured fact retrieval FastAPI React TypeScript Ollama

📄 Publications


🧰 Tech Stack

Languages    Python R TypeScript JavaScript

ML & Data    scikit-learn PyTorch Polars MLflow

Bioinformatics    Scanpy SAMtools Minimap2 AnnData

Viz & Frontend    Three.js D3.js SvelteKit Plotly

Pipelines & Cloud    Nextflow Docker AWS Singularity

AI Dev    Claude Kiro Cursor GitHub Copilot


GitHub Streak

From chromosomes to constellations — decoding biology, one pipeline at a time. 🧬✨

Pinned Loading

  1. genBrowser genBrowser Public

    Interactive 3D chromosome visualization dashboard built with Three.js and TypeScript. Maps biological metrics (GC content, surface accessibility, radial distance) onto a chromosome 1 structural mod…

    Python 3

  2. chromApipe chromApipe Public

    A Nextflow pipeline for integrating 3D chromosome structure with genomic annotations and physical features

    Nextflow 1

  3. tanav2202/PolicyLens tanav2202/PolicyLens Public

    Python 3

  4. spaceGen spaceGen Public

    NASA GeneLab mouse RNA-seq pipeline — medallion lakehouse architecture, ML modeling with MLflow tracking

    Jupyter Notebook