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feat: default min_frac_accessible to 0.10 - #66

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feat-min-frac-accessible
Aug 14, 2026
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feat: default min_frac_accessible to 0.10#66
mrvollger merged 1 commit into
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feat-min-frac-accessible

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@mrvollger mrvollger commented Aug 14, 2026

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Split out of #62. FIRE peaks must now have at least 10% of reads accessible (fire_coverage/coverage >= 0.10, applied in merge_fire_peaks.py) in addition to passing FDR peak calling. Set min_frac_accessible: 0.0 to restore the old behavior.

On the test dataset this removes no peaks (all peaks there exceed 19% accessibility), so test outputs are unchanged; on real WGS data marginal peaks will be filtered.

FIRE peaks now require >=10% of reads accessible on top of FDR peak
calling by default; set min_frac_accessible: 0.0 for the old behavior.

Co-Authored-By: Claude Fable 5 <noreply@anthropic.com>
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mrvollger merged commit 2f52149 into main Aug 14, 2026
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mrvollger deleted the feat-min-frac-accessible branch August 14, 2026 00:59
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