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Find Nuclei Viewer

Browser-based viewer for OME-ZARR (OME-NGFF) microscopy data with GPU-accelerated rendering.

Pre-release · Launch Viewer · Documentation · Watch Demos · Embed in Your Site


Features

Opening data

  • Local files, straight from disk. No upload and no server. Browse ZARR folders on your own machine and the data never leaves it.
  • Remote URLs. Anything served over HTTPS with CORS and range requests: S3, R2, GCS, Azure Blob, your own nginx.

Looking at it

  • Multi-channel display with per-channel colour, contrast, gamma and histograms.
  • Auto-contrast from the pixel data, percentile based (2% to 98%), one click per channel or all at once.
  • Grayscale and inverted modes. Inverted flips the backgroud and pixel intensity, which prints well and makes a coloured mask overlay far easier to read.
  • Z-projection: maximum, mean and minimum, over a Z-range you choose.
  • GPU-accelerated tiled rendering via deck.gl WebGL, comfortable on images past 100,000 pixels a side.
  • HCS plates. Well picker grid, field view and plate overview for 96, 384 and 1536-well screens.

Working with it

  • Annotations. Polygons, lines, points and distance measurements, with areas and lengths in real units. Auto-saved to browser storage, exportable as CSV or GeoJSON.
  • Segmentation labels. Load them from inside the ZARR or attach them from a local folder or a URL. Opacity, colour modes, drag to reorder.
  • Analytics and phenotyping. Attach a measurements table and colour objects by any column, as a continuous heatmap or one colour per category. Filter by value, and build named phenotype groups out of those filters.
  • Annotation templates. Reusable bundles of colour, class label and keyboard shortcut, applied to everything you draw next.
  • Shareable deep links. The URL tracks zoom, position, channels and Z-slice as you work, Google Maps style. Copy it to hand someone the exact view.

Throughout

  • Privacy first, zero install. Everything happens in your browser. No account, and no data sent anywhere.

Documentation

Full guides at find-nuclei.github.io/docs.

Getting Started Open your first image
Local Files · Remote URLs · Authenticated Sources Getting data in
Channels · HCS Plates Display and navigation
Labels · Analytics & Phenotyping · Analytics Data Format Segmentation and measurements
Annotations · Templates Drawing regions
Sharing Views · Embedding · Data Server Publishing and hosting

Live Examples

Click any link to open directly in the viewer:

Example Description
Nuclear segmentation, labels on Image plus its segmentation mask, coloured per object
Chicken Embryo MIP v0.5 sharded, single channel
Zebrafish Lateral Line 3D multi-channel with labels
HCS Plate 190129 v0.5 multi-well plate, 5 channels
HCS Plate 9512 v0.4 multi-well plate, 2 channels
Large Image 9822152 144K×93K pixels, multi-resolution
RGB Image 9798462 3-channel RGB, 21K×16K

All datasets from the Image Data Resource (IDR), read straight from its public bucket. Nothing is copied or re-hosted.


Embeddable Viewer for Publications

Embed an interactive OME-ZARR viewer in any web page with two lines of HTML:

<script src="https://find-nuclei.github.io/embed/v1/viewer.js"></script>

<find-nuclei-viewer
  url="https://uk1s3.embassy.ebi.ac.uk/idr/zarr/v0.4/idr0062A/6001240.zarr"
  labels="on"
  width="100%"
  height="500"
></find-nuclei-viewer>

No iframe, no build step, no framework required. Works in any CMS (WordPress, Drupal, Ghost, PubPub). Full style isolation via Shadow DOM.


Use Cases

  • Digital Pathology: whole slide imaging (WSI) for H&E and IHC slides
  • Spatial Biology & Multiplexed Imaging: multi-channel IF, CODEX, MERFISH, seqFISH
  • High-Content Screening: automated 96/384/1536-well plate imaging
  • Confocal & Light-Sheet Microscopy: Z-stacks and time-lapse live-cell imaging
  • Electron Microscopy: serial-section TEM and volume EM for connectomics
  • Super-Resolution Microscopy: STORM, PALM, SIM
  • Spatial Transcriptomics: Visium, Slide-seq, MERSCOPE
  • Organoid & Spheroid Imaging: 3D cell culture with Z-stack support
  • Live-Cell Imaging: dynamic cellular processes over time
  • Tissue Clearing & 3D Imaging: CLARITY, iDISCO

Requirements

  • Format: OME-ZARR (OME-NGFF) v0.4 and v0.5, including sharded stores, plus bioformats2raw layouts.
  • Any modern browser for remote URLs, including Firefox and Safari.
  • Chrome or Edge to open files and folders from disk. That path uses the File System Access API, which the other browsers do not implement yet.

Privacy

All data is processed locally in your browser. No files are uploaded to any server.


License

Copyright (c) 2026 Find Nuclei. All rights reserved.

For licensing inquiries: info@find-nuclei.com


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Browser-based OME-ZARR microscopy viewer. Open local files, annotate, overlay segmentation labels, share deep links. GPU-accelerated, privacy-first, zero-install.

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